Uncapped 19-year-old opener Nauman Anwar and former under-19 captain Imad Wasim were given call-ups.
Meanwhile, Saeed Ajmal, who was ineffective with his new bowling action, was dropped along with Sohail Tanvir.
Both Sohaib Maqsood and Sohail Khan were sidelined over fitness issues, and Junaid Khan was the other notable exclusion for the Zimbabwe series.
